Access of the Substrate to the Active Site of Yeast Oxidosqualene Cyclase: An Inhibition and Site-Directed Mutagenesis Approach
Author:
Publisher
Wiley
Subject
Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry
Reference35 articles.
1. Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes
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4. Synthesis and Structure−Activity Studies of Novel Orally Active Non-Terpenoic 2,3-Oxidosqualene Cyclase Inhibitors
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2. A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin;Plant Physiology;2017-12-04
3. Friedelin Synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Role in the Production of the Most Rearranged Pentacyclic Triterpene;Scientific Reports;2016-11-22
4. A conserved amino acid residue critical for product and substrate specificity in plant triterpene synthases;Proceedings of the National Academy of Sciences;2016-07-13
5. The triterpene cyclase protein family: A systematic analysis;Proteins: Structure, Function, and Bioinformatics;2012
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