Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant-Reference-Cited by-同舟云学术

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Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant

Published:2013-05 Issue:20 Volume:31 Page:2457-2464
ISSN:0264-410X
Container-title:Vaccine
language:en
Short-container-title:Vaccine

Author:

Holmgren J.,Bourgeois L.,Carlin N.,Clements J.,Gustafsson B.,Lundgren A.,Nygren E.,Tobias J.,Walker R.,Svennerholm A.-M.

Funder

PATH, the Swedish Research Council

Västra Götaland Region ALF funds

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference35 articles.

1. Enterotoxigenic Escherichia coli in developing countries: epidemiology, microbiology, clinical features, treatment, and prevention;Qadri;Clin Microbiol Rev,2005

2. Colonization factors of human enterotoxigenic Escherichia coli (ETEC);Gaastra;Trends Microbiol,1996

3. Crossprotection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile toxin-producing enterotoxigenic Escherichia coli: results of a large-scale field trial;Clemens;J Infect Dis,1988

4. Disease burden due to enterotoxigenic Escherichia coli in the first 2 years of life in an urban community in Bangladesh;Qadri;Infect Immun,2007

5. From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development;Svennerholm;Indian J Med Res,2011

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