Fighting fire with fire: Extracellular vesicles from pyroptotic mesenchymal stromal cells can dampen inflammation during sepsis
Author:
Funder
National Health and Medical Research Council
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine
Reference9 articles.
1. Shattering barriers toward clinically meaningful MSC therapies;Levy;Sci. Adv.,2020
2. Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?;Kou;Cell Death Dis.,2022
3. Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation;Galleu;Sci. Transl. Med.,2017
4. Mesenchymal stromal cell apoptosis is required for their therapeutic function;Pang;Nat. Commun.,2021
5. ASC-expressing pyroptotic extracellular vesicles alleviate sepsis by protecting B cells;Huang;Mol. Ther.,2023
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