Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation-Reference-Cited by-同舟云学术

Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation

Published:2017-11-15 Issue:416 Volume:9 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Galleu Antonio¹^ORCID,Riffo-Vasquez Yanira²^ORCID,Trento Cristina¹,Lomas Cara³⁴^ORCID,Dolcetti Luigi¹^ORCID,Cheung Tik Shing¹^ORCID,von Bonin Malte⁵,Barbieri Laura¹^ORCID,Halai Krishma¹,Ward Sophie³⁴^ORCID,Weng Ling¹,Chakraverty Ronjon³⁴,Lombardi Giovanna⁶^ORCID,Watt Fiona M.⁷^ORCID,Orchard Kim⁸^ORCID,Marks David I.⁹,Apperley Jane¹⁰,Bornhauser Martin¹⁵,Walczak Henning⁴^ORCID,Bennett Clare³⁴^ORCID,Dazzi Francesco¹¹⁰^ORCID

Affiliation:

1. Regenerative Medicine, Division of Cancer Studies and Cancer Research UK King’s Health Partners, King’s College London, London SE5 9NU, UK.

2. Institute of Pharmaceutical Science, King’s College London, London SE1 9NH, UK.

3. Institute of Immunity and Transplantation, University College London, London NW3 2QG, UK.

4. Cancer Institute, University College London, London WC1E 6DD, UK.

5. University Hospital Carl Gustav Carus, 01307 Dresden, Germany.

6. Medical Research Council Centre for Transplantation, King’s College London, London SE1 9RT, UK.

7. Centre for Stem Cells and Regenerative Medicine, King’s College London, London SE1 9RT, UK.

8. University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.

9. Bristol Haematology and Oncology Centre, Bristol BS2 8ED, UK.

10. Centre for Haematology, Imperial College London, London W12 0NN, UK.

Abstract

Mesenchymal stromal cell apoptosis, induced in vivo by recipient cytotoxic cells, is required for immunosuppression and clinical responses.

Funder

Bloodwise

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference57 articles.

1. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide

2. Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease

3. Mesenchymal stem cells and autoimmune diseases

4. Mesenchymal Stromal Cells for Treatment of Acute Steroid-Refractory Graft Versus Host Disease: Clinical Responses and Long-Term Outcome

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