Discovery of orally bioavailable NK1 receptor antagonists-Reference-Cited by-同舟云学术

Discovery of orally bioavailable NK1 receptor antagonists

Published:2003-02 Issue:3 Volume:13 Page:437-442
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Genicot C.,Christophe B.,Collart P.,Gillard M.,Goossens L.,Hénichart J.-P.,Lassoie M.-A.,Moureau F.,Neuwels M.,Nicolas J.-M.,Pasau P.,Quéré L.,Ryckmans T.,Stiernet F.,Taverne T.,Van Keulen B.J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference12 articles.

1. Substance P: a pioneer amongst neuropeptides

2. Discovery of a potent substance P antagonist: recognition of the key molecular determinant

3. Piperidine-ether based hNK1 antagonists 1: Determination of the relative and absolute stereochemical requirements

4. Structural Optimization Affording 2-(R)-(1-(R)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

5. Synthesis and structure-activity relationships of CP-122,721, a second-generation NK-1 receptor antagonist

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