5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms-Reference-Cited by-同舟云学术

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5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

Published:2016-08 Issue:16 Volume:24 Page:3790-3800
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Orban Oliver C.F.,Korn Ricarda S.,Benítez Diego,Medeiros Andrea,Preu Lutz,Loaëc Nadège,Meijer Laurent,Koch Oliver,Comini Marcelo A.,Kunick Conrad

Funder

German Federal Ministry of Education and Research

FOCEM

ANII

Agence Nationale de la Recherche

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference52 articles.

1. WHO. Neglected Tropical Diseases: (accessed May 29, 2015).

2. Drug resistance in leishmaniasis

3. Evidence that the High Incidence of Treatment Failures in Indian Kala‐Azar Is Due to the Emergence of Antimony‐Resistant Strains ofLeishmania donovani

4. Recent Approaches to Chemical Discovery and Development Against Malaria and the Neglected Tropical Diseases Human African Trypanosomiasis and Schistosomiasis

5. Recent Developments in Drug Discovery for Leishmaniasis and Human African Trypanosomiasis

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1. Targeting Trypanothione Metabolism in Trypanosomatids;Molecules;2024-05-09

2. The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones;PLOS ONE;2023-11-30

3. Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction–Optimization Strategy Applied to Paullones;ChemMedChem;2023-03-28

4. An Effective Synthesis of Previously Unknown 7-Aryl Substituted Paullones;Molecules;2023-03-02

5. Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening;Journal of Enzyme Inhibition and Medicinal Chemistry;2022-03-21

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