Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening-Reference-Cited by-同舟云学术

Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening

Published:2022-03-21 Issue:1 Volume:37 Page:912-929
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Benítez Diego¹,Franco Jaime¹,Sardi Florencia¹,Leyva Alejandro²,Durán Rosario²,Choi Gahee³,Yang Gyongseon³,Kim Taehee⁴,Kim Namyoul⁴,Heo Jinyeong⁴,Kim Kideok⁵,Lee Honggun⁵,Choi Inhee⁶,Radu Constantin⁵,Shum David⁴,No Joo Hwan³,Comini Marcelo A.¹

Affiliation:

1. Laboratory Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay

2. Analytical Biochemistry and Proteomics Unit, Institut Pasteur de Montevideo, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay

3. Host-Parasite Research Laboratory, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea

4. Assay Development and Screening, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea

5. Automation and Logistics Management, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea

6. Medicinal Chemistry, Institut Pasteur Korea, Gyeonggi-do, Republic of Korea

Funder

Le Réseau International des Instituts Pasteur (RIIP)”, "Actions Concertees Internacionales Pasteuriennes

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756366.2022.2045590

Reference69 articles.

1. WHO. Research priorities for Chagas disease, Human African Trypanosomiasis and Leishmaniasis. Technical report of the TDR disease reference group on Chagas disease, Human African Trypanosomiasis and Leishmaniasis. Technical Report 2012. https://apps.who.int/iris/handle/10665/77472

2. Trypanothione-Based Redox Metabolism of Trypanosomatids

3. The ATP-grasp enzymes

4. Biosynthesis of Polyamine–Glutathione Derivatives in Enterobacteria and Kinetoplastida

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