In vitro structure–activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety–depression model-Reference-Cited by-同舟云学术

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In vitro structure–activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety–depression model

Published:2013-11 Issue:22 Volume:21 Page:7083-7090
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Lewellyn Kevin,Bialonska Dobroslawa,Loria Melissa J.,White Stephen W.,Sufka Kenneth J.,Zjawiony Jordan K.

Funder

National Institute of General Medical Sciences (NIGMS)

National Institutes of Health (NIH

NIH National Center for Research Resources

National Institute of Mental Health’s Psychoactive Drug Screening Program (NIMH PDSP)

NIMH, Bethesda MD, USA

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference40 articles.

1. Aplysinopsin, a new tryptophan derivative from a sponge

2. Tryptophan Derivatives from a Mediterranean Anthozoan, Astroides calycularis

3. Marine natural products: the past twenty years and beyond

4. Characterization of Compounds That Induce Symbiosis Between Sea Anemone and Anemone Fish

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1. Synthesis and in vitro evaluation of novel amino-phenylmethylene-imidazolone 5-HT_2A receptor antagonists;RSC Medicinal Chemistry;2024

2. An Overview of Aplysinopsins: Synthesis and Biological Activities;Marine Drugs;2023-04-26

3. Synthetic Analogs of Marine Alkaloid Aplysinopsin Suppress Anti-Apoptotic Protein BCL2 in Prostate Cancer;Molecules;2022-12-23

4. Physicochemical, Interaction & Topological Descriptors vs. hMAO-A Inhibition of Aplysinopsin Analogs: A Boulevard to the Discovery of Semi-synthetic Antidepression Agents;Current Drug Metabolism;2021-09

5. Identification of aplysinopsin as a blood-brain barrier permeable scaffold for anti-cholinesterase and anti-BACE-1 activity;Bioorganic Chemistry;2021-02

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