Affiliation:
1. Chemistry of Natural Compounds Department, National Research Centre, Giza 12622, Egypt
2. Laboratoire Lorrain de Chimie Moléculaire (L.2.C.M.), Université de Lorraine, 57050 Metz, France
Abstract
Marine products are among the most promising sources of biologically active molecules. Aplysinopsins, tryptophan-derived marine natural products, were isolated from different natural marine sources including sponges, stony corals (hard corals) especially genus scleractinian, as well as sea anemone, in addition to one nudibranch. Aplysinopsins were reported to be isolated from different marine organisms related to various geographic areas such as Pacific, Indonesia, Caribbean, and Mediterranean regions. This review gives an up-to-date overview of marine alkaloid aplysinopsins: their various sources, their synthesis, and the fact that many aplysinopsin derivatives are biologically active compounds.
Subject
Drug Discovery,Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science
Reference50 articles.
1. Promising bioactive compounds from the marine environment and their potential effects on various diseases;Karthikeyan;J. Genet. Eng. Biotechnol.,2022
2. Bialonska, D., and Zjawiony, J.K. (2009). Aplysinopsins—Marine Indole Alkaloids: Chemistry, Bioactivity and Ecological Significance. Mar. Drugs, 7.
3. Aplysinopsin, a new tryptophan derivative from a sponge;Kazlauskas;Tetrahedron Lett.,1977
4. Aplysinopsin: Antineoplastic Tryptophan Derivative from the Marine Sponge Verongia Spengelii;Kh;Lloydia,1977
5. Metabolites of the marine sponge Dercitus species;Djura;J. Org. Chem.,1980
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