Synthesis and SAR study of 4,5-diaryl-1H-imidazole-2(3H)-thione derivatives, as potent 15-lipoxygenase inhibitors-Reference-Cited by-同舟云学术

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Synthesis and SAR study of 4,5-diaryl-1H-imidazole-2(3H)-thione derivatives, as potent 15-lipoxygenase inhibitors

Published:2012-12 Issue:24 Volume:20 Page:7160-7166
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Assadieskandar Amir,Amini Mohsen,Salehi Marjan,Sadeghian Hamid,Alimardani Maliheh,Sakhteman Amirhossein,Nadri Hamid,Shafiee Abbas

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference41 articles.

1. Phospholipid Methylation and Biological Signal Transmission

2. Introduction: lipids as regulators of cell function

3. Lipoxygenases (LOs): An Heterogenous Family of Lipid Peroxidizing Enzymes Implicated in Cell Differentiation, Inflammation, Asthma, Carcinogenesis, Atherogenesis-An Interesting Target for the Development of Promising Drugs

4. Leukotriene-Receptor Antagonists and 5-Lipoxygenase Inhibitors in Asthma

5. Three-Dimensional Structure of a Purple Lipoxygenase

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4. New imidazo[1,2-a]pyridin-2-yl derivatives as AChE, BChE and 15-LOX inhibitors; design, synthesis, and biological evaluation;Letters in Drug Design & Discovery;2022-06-08

5. Heteroannulation Reaction of α-Aminoketones for the Efficient Synthesis of 4-Imidazolin-2-ones and 2-Thiones;Journal of the Brazilian Chemical Society;2022

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