Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference72 articles.
1. Inflammatory responses and inflammation-associated diseases in organs;Chen;Oncotarget,2018
2. Points of control in inflammation;Nathan;Nature,2002
3. Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets;Wang;Signal Transduct. Targeted Ther.,2021
4. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression;Chandrasekharan;Proc. Natl. Acad. Sci. U. S. A.,2002
5. Distinct functions of COX-1 and COX-2
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Design, synthesis and anti-inflammatory assessment of certain substituted 1,2,4-triazoles bearing tetrahydroisoquinoline scaffold as COX 1/2-inhibitors;Bioorganic Chemistry;2024-09
2. Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study;Bioorganic Chemistry;2024-04
3. Exploring the Action Mechanism and Validation of the Key Pathways of Dendrobium officinale Throat-clearing Formula for the Treatment of Chronic Pharyngitis Based on Network Pharmacology;Combinatorial Chemistry & High Throughput Screening;2024-02
4. Antimicrobial Evaluation of Sulfonamides after Coupling with Thienopyrimidine Coplanar Structure;Pharmaceuticals;2024-01-31
5. Anti-inflammatory Activity and Computational Biology Study of Indole/Pyrimidine Hybrids;Current Organic Chemistry;2024-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3