Discovery of pyrrolo[3,2-c]quinoline-4-one derivatives as novel hedgehog signaling inhibitors-Reference-Cited by-同舟云学术

Discovery of pyrrolo[3,2-c]quinoline-4-one derivatives as novel hedgehog signaling inhibitors

Published:2012-09 Issue:18 Volume:20 Page:5496-5506
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ohashi Tomohiro,Oguro Yuya,Tanaka Toshio,Shiokawa Zenyu,Shibata Sachio,Sato Yoshihiko,Yamakawa Hiroko,Hattori Harumi,Yamamoto Yukiko,Kondo Shigeru,Miyamoto Maki,Tojo Hideaki,Baba Atsuo,Sasaki Satoshi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. A freely diffusible form of Sonic hedgehog mediates long-range signalling

2. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

3. Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

4. Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade

5. Basal cell carcinomas: attack of the hedgehog

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