Rh(<scp>iii</scp>)-catalyzed highly site- and regio-selective alkenyl C–H activation/annulation of 4-amino-2-quinolones with alkynes <i>via</i> reversible alkyne insertion-Reference-Cited by-同舟云学术

Rh(iii)-catalyzed highly site- and regio-selective alkenyl C–H activation/annulation of 4-amino-2-quinolones with alkynes via reversible alkyne insertion

Published:2023 Issue:39 Volume:14 Page:10971-10978
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Hirako Naohiro¹,Yasui Takeshi¹^ORCID,Yamamoto Yoshihiko¹^ORCID

Affiliation:

1. Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho Chikusa, Nagoya 464-8603, Japan

Abstract

A practical approach for preparing 3,4-fused 2-quinolones has been disclosed. The Rh(iii)-catalyzed highly selective alkenyl C–H activation/annulation of 4-amino-2-quinolones was achieved via an unprecedented reversible alkyne insertion.

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03987K

Reference57 articles.

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