3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT)-Reference-Cited by-同舟云学术

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3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT)

Published:2010-11 Issue:21 Volume:18 Page:7659-7667
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Kovac Mitja,Mavel Sylvie,Deuther-Conrad Winnie,Méheux Nathalie,Glöckner Jana,Wenzel Barbara,Anderluh Marko,Brust Peter,Guilloteau Denis,Emond Patrick

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference53 articles.

1. Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

2. Ex vivo and in vivo evaluation of (2R,3R)-5-[18F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter

3. Positron emission tomography imaging of (2R,3R)-5-[18F]fluoroethoxybenzovesamicol in rat and monkey brain: a radioligand for the vesicular acetylcholine transporter

4. Synthesis of [18F]fluoroethoxy-benzovesamicol, a radiotracer for cholinergic neurons

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1. Computational modeling of PET imaging agents for vesicular acetylcholine transporter (VAChT) protein binding affinity: application of 2D-QSAR modeling and molecular docking techniques;In Silico Pharmacology;2023-04-04

2. Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development;Pharmaceuticals;2023-02-18

3. Development and preclinical evaluation of [18F]FBVM as a new potent PET tracer for vesicular acetylcholine transporter;European Journal of Medicinal Chemistry;2022-12

4. Discovery and Design of Radiopharmaceuticals by In silico Methods;Current Radiopharmaceuticals;2022-12

5. Forgotten and forbidden chemical reactions revitalised through continuous flow technology;Organic & Biomolecular Chemistry;2021

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