A computer-aided drug design approach to discover tumour suppressor p53 protein activators for colorectal cancer therapy-Reference-Cited by-同舟云学术

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A computer-aided drug design approach to discover tumour suppressor p53 protein activators for colorectal cancer therapy

Published:2022-01 Issue: Volume:53 Page:116530
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Patrício Rui P.S.,Videira Paula A.,Pereira Florbela

Funder

Fundacao para a Ciencia e a Tecnologia

European Commission Sixth Framework Programme

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference66 articles.

1. P53 – Oncogene or anti-oncogene;Lane;Genes Dev,1990

2. How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?;Aubrey;Cell Death Differ,2018

3. Medicinal chemistry strategies to disrupt the p53-MDM2/MDMX interaction;Lemos;Med Res Rev,2016

4. p53 mutations in colorectal cancer- molecular pathogenesis and pharmacological reactivation;Li;World J Gastroenterol,2015

5. Targeting mutant p53 for efficient cancer therapy;Bykov;Nat Rev Cancer,2018

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