A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method-Reference-Cited by-同舟云学术

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A novel assessment of nefazodone-induced hERG inhibition by electrophysiological and stereochemical method

Published:2014-02 Issue:3 Volume:274 Page:361-371
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Shin Dae-Seop,Park Myoung Joo,Lee Hyang-Ae,Lee Joo Yun,Chung Hee-Chung,Yoo Dae Seok,Chae Chong Hak,Park Sang-Joon,Kim Ki-Suk,Bae Myung Ae

Funder

Ministry of Knowledge and Economy

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference76 articles.

1. Assessment of QT liabilities in drug development;Arrigoni;Cell Biol. Toxicol.,2007

2. HERG binding specificity and binding site structure: evidence from a fragment-based evolutionary computing SAR study;Bains;Prog. Biophys. Mol. Biol.,2004

3. Cardiac arrest in a young woman with the long QT syndrome and concomitant astemizole ingestion;Broadhurst;Br. Heart J.,1993

4. Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers;Cavalli;J. Med. Chem.,2002

5. The long QT syndromes: genetic basis and clinical implications;Chiang;J. Am. Coll. Cardiol.,2000

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1. G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders;Signal Transduction and Targeted Therapy;2023-05-03

2. The molecular determinants of R-roscovitine block of hERG channels;PLOS ONE;2019-09-03

3. Removal of hERG potassium channel affinity through introduction of an oxygen atom: Molecular insights from structure-activity relationships of strychnine and its analogs;Toxicology and Applied Pharmacology;2018-12

4. Structural investigation of vesnarinone at the pore domains of open and open-inactivated states of hERG1 K + channel;Journal of Molecular Graphics and Modelling;2017-10

5. In silico design of novel hERG-neutral sildenafil-like PDE5 inhibitors;Journal of Biomolecular Structure and Dynamics;2016-10-06

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