Toward a Pharmacophore for Drugs Inducing the Long QT Syndrome: Insights from a CoMFA Study of HERG K+ Channel Blockers-Reference-Cited by-同舟云学术

Toward a Pharmacophore for Drugs Inducing the Long QT Syndrome: Insights from a CoMFA Study of HERG K+ Channel Blockers

Published:2002-07-25 Issue:18 Volume:45 Page:3844-3853
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cavalli Andrea¹,Poluzzi Elisabetta¹,De Ponti Fabrizio¹,Recanatini Maurizio¹

Affiliation:

1. Department of Pharmaceutical Sciences, University of Bologna, Via Belmeloro 6, I-40126 Bologna, Italy, and Department of Pharmacology, University of Bologna, Via Irnerio 48, I-40126 Bologna, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0208875

Reference32 articles.

1. Long QT syndromes and torsade de pointes

2. QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience

3. Points to consider: the assessment of the potential for QT interval prolongation by noncardiovascular medicinal products; European Agency for the Evaluation of Medicinal Products (EMEA): Committee for Proprietary Medicinal Products (CPMP), 1997.

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