Lack of DNA-damaging activity of five non-nutritive sweeteners in the rat hepatocyte/DNA repair assay

Author:

Jeffrey A.M,Williams G.M

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference20 articles.

1. The genotoxicity of sodium saccharin and sodium chloride in relation to their cancer-promoting properties;Ashby;Food and Chemical Toxicology,1985

2. Further validation of FETAX: evaluation of the developmental toxicity of five known mammalian teratogens and non-teratogens;Bantle;Drug and Chemical Toxicology,1990

3. Food and Drug Administration 21 CFR Part 172. Food Additives Permitted for Direct Addition to Food for Human Consumption; Sucralose;Federal Register,1988

4. Effects of three sweeteners on rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine;Hagiwara;Gann,1984

5. Strain differences in in vitro rat hepatocyte unscheduled DNA synthesis (UDS): effect of UV is independent of strain while increased sensitivity is apparent using Fischer-344 instead of Sprague-Dawley rats;Harbach;Mutation Research,1991

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