ortho-Halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity

Author:

Ghelli Stefano,Rinaldi Marcella,Barlocco Daniela,Gelain Arianna,Pecorari Piergiorgio,Tondi Donatella,Rastelli Giulio,Costi Maria Paola

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference40 articles.

1. Santi, D. V.; Danenberg, P. V. Folate and Pteridines: Vol. 1, Chemistry and Biochemistry of Folates. Blakely, R. L., Benkovic, S. J., Eds.; John Wiley & Sons: New York, 1984; p. 345.

2. The thymidylate synthesis cycle and anticancer drugs

3. Thymidylate synthase inhibition: A structure-based rationale for drug design

4. Structure-Based Design of Inhibitors Specific for Bacterial Thymidylate Synthase,

5. Phthalein Derivatives as a New Tool for Selectivity in Thymidylate Synthase Inhibition

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