Phthalein Derivatives as a New Tool for Selectivity in Thymidylate Synthase Inhibition-Reference-Cited by-同舟云学术

Phthalein Derivatives as a New Tool for Selectivity in Thymidylate Synthase Inhibition

Published:1999-05-29 Issue:12 Volume:42 Page:2112-2124
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Costi Paola M.¹,Rinaldi Marcella¹,Tondi Donatella¹,Pecorari Piergiorgio¹,Barlocco Daniela¹,Ghelli Stefano¹,Stroud Robert M.¹,Santi Daniel V.¹,Stout Thomas J.¹,Musiu Chiara¹,Marangiu Elena M.¹,Pani Alessandra¹,Congiu Donatella¹,Loi Giulia A.¹,La Colla Paolo¹

Affiliation:

1. Dipartimento Scienze Farmaceutiche and Dipartimento Scienze Chimiche, Università di Modena e Reggio Emilia, Via Campi 183, 41100 Modena, Italy, Istituto Chimica Farmacologia e Tossacologia, Università Milano, Viale Abruzzi 42, 20131 Milano, Italy, Departments of Biochemistry and Biophysics and of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, and Dipartimento Biologia Sperimentale, Università di Cagliari, v.le Regina Margherita 45, 09214 Cagliari, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9900016

Reference39 articles.

1. The thymidylate synthesis cycle and anticancer drugs

2. Site-directed Mutagenesis of Varicella-zoster Virus Thymidylate Synthase. Analysis of Two Highly Conserved Regions of the Enzyme

3. Santi, D. V.; Danenberg, P. V. InFolates and Pterins: Vol. 1, Folate inPyrimidine Nucleotide Biosynthesis; Blakley, R. L., Benkovic, S. J., Eds.; John Wiley & Sons: New York, 1984; pp 345−399.

4. THE CATALYTIC MECHANISM AND STRUCTURE OF THYMIDYLATE SYNTHASE

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