Intersite communication in dimeric enzymes highlighted by structural and thermodynamic analysis of didansyltyrosine binding to thymidylate synthases-Reference-Cited by-同舟云学术

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Intersite communication in dimeric enzymes highlighted by structural and thermodynamic analysis of didansyltyrosine binding to thymidylate synthases

Published:2024-10 Issue: Volume:151 Page:107663
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Venturelli Alberto,Guaitoli Giambattista,Vanossi Davide,Saitta Francesca,Fessas Dimitrios,Vitiello Simone,Malpezzi Giulia,Aiello Daniele,Ferrari Stefania,Tondi Donatella,Ponterini Glauco,Paola Costi Maria

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Elsevier BV

Reference27 articles.

1. Standing the test of time: targeting thymidylate biosynthesis in cancer therapy;Wilson;Nat. Rev. Clin. Oncol.,2014

2. Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase;Luciani;J. Med. Chem.,2016

3. The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent;Bré;Cancer Chemother. Pharmacol.,2023

4. Phthalein derivatives as a new tool for selectivity in thymidylate synthase inhibition;Costi;J. Med. Chem.,1999

5. Antibacterial agent discovery using thymidylate synthase biolibrary screening;Costi;J. Med. Chem.,2006

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