Leishmania major parasites induced macrophage tolerance: Implication of MAPK and NF-κB pathways

Author:

Ben-Othman Rym,Dellagi Koussay,Guizani-Tabbane Lamia

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference27 articles.

1. Leishmania initially activates but subsequently down-regulates intracellular mitogen-activated protein kinases and nuclear factor-kappaB signaling in macrophages;Ben-Othman;Mol. Immunol.,2008

2. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance;Berg;J. Clin. Invest.,1995

3. Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice;Carrera;J. Exp. Med.,1996

4. Leishmania major-parasitized macrophages augment Th2-type T cell activation;Chakkalath;J. Immunol.,1994

5. Enhancement of macrophage IL-1 production by Leishmania major infection in vitro and its inhibition by IFNg;Cillari;J. Immunol.,1989

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