Therapeutic targeting of RAS: New hope for drugging the “undruggable”
Author:
Funder
U.S. Department of Veterans Affairs
National Institutes of Health
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference181 articles.
1. Ras oncogenes and their downstream targets;Rajalingam;Biochim. Biophys. Acta,2007
2. Ras oncogenes: split personalities;Karnoub;Nat Rev Mol Cell Biol,2008
3. Targeting RAS signalling pathways in cancer therapy;Downward;Nat. Rev. Cancer,2003
4. Direct inhibition of RAS: quest for the holy grail?;Spencer-Smith;Semin. Cancer Biol.,2019
5. Pharmacological targeting of RAS: recent success with direct inhibitors;O’Bryan;Pharmacol. Res.,2019
Cited by 84 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Targeting the RAS upstream and downstream signaling pathway for cancer treatment;European Journal of Pharmacology;2024-09
2. Probing the Electrostatic Effects of H-Ras Tyrosine 32 Mutations on Intrinsic GTP Hydrolysis Using Vibrational Stark Effect Spectroscopy of a Thiocyanate Probe;Biochemistry;2024-07-05
3. Targeting KRASG12C in Non-Small-Cell Lung Cancer: Current Standards and Developments;Drugs;2024-04-16
4. Temporal trends and regional variability in BRAF and KRAS genetic testing in Denmark (2010–2022): Implications for precision medicine;Genes, Chromosomes and Cancer;2024-04
5. DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-Ras;PLOS ONE;2024-03-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3