Pharmacological targeting of RAS: Recent success with direct inhibitors
Author:
Funder
United States (US) Department of Veterans Affairs Biomedical Laboratory Research and Development Service and NIH awards
Publisher
Elsevier BV
Subject
Pharmacology
Reference116 articles.
1. Stable suppression of tumorigenicity by virus-mediated RNA interference;Brummelkamp;Cancer Cell,2002
2. Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance;Lim;Cancer Cell,2005
3. A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival;Singh;Cancer Cell,2009
4. Long-term ERK inhibition in KRAS-mutant pancreatic cancer is associated with MYC degradation and senescence-like growth suppression;Hayes;Cancer Cell,2016
5. Essential role for oncogenic Ras in tumour maintenance;Chin;Nature (London),1999
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