Ligand-based computer aided drug design reveals new tropomycin receptor kinase a (TrkA) inhibitors

Author:

Shahin Rand,Mansi Iman,Swellmeen Lubna,Alwidyan Tahani,Al-Hashimi Nabil,Al-Qarar’h Yaser,Shaheen Omar

Funder

Deanship of Scientific Research in Hashemite University

Deanship of Scientific Research in Zarqa University

Publisher

Elsevier BV

Subject

Materials Chemistry,Computer Graphics and Computer-Aided Design,Physical and Theoretical Chemistry,Spectroscopy

Reference60 articles.

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2. Trk kinase inhibitors as new treatments for cancer and pain;Wang;Expert Opin. Ther. Pat.,2009

3. The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition;Bertrand;J. Mol. Biol.,2012

4. Trk receptor tyrosine kinases: a bridge between cancer and neural development;Nakagawara;Cancer Lett.,2001

5. Nerve growth factor & TrkA as novel therapeutic targets in cancer;Demir;Biochim. Biophys. Acta – Rev. Cancer.,1866

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