High-performance liquid chromatographic method for the detection and quantitation of haloperidol and seven of its metabolites in microsomal preparations-Reference-Cited by-同舟云学术

High-performance liquid chromatographic method for the detection and quantitation of haloperidol and seven of its metabolites in microsomal preparations

Published:1993-05 Issue:2 Volume:614 Page:267-273
ISSN:0378-4347
Container-title:Journal of Chromatography B: Biomedical Sciences and Applications
language:en
Short-container-title:Journal of Chromatography B: Biomedical Sciences and Applications

Author:

Fang Jian,Gorrod John W.

Publisher

Elsevier BV

Subject

General Chemistry

Reference24 articles.

1. Distribution, excretion and metabolism of neuroleptics of the butyrophenone type

2. Identification of a potentially neurotoxic pyridinium metabolite of haloperidol in rats

3. Studies on the in vitro conversion of haloperidol to a potentially neurotoxic pyridinium metabolite

4. Dehydration is the first step in the bioactivation of haloperidol to its pyridinium metabolite

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