Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis-Reference-Cited by-同舟云学术

Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis

Published:2018-02 Issue:4 Volume:69 Page:699-708.e7
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Zhao Dongxin,Badur Mehmet G.,Luebeck Jens,Magaña Jose H.,Birmingham Amanda,Sasik Roman,Ahn Christopher S.,Ideker Trey,Metallo Christian M.,Mali Prashant

Funder

California Institute of Regenerative Medicine

NIH

Camille and Henry Dreyfus Teacher-Scholar

NSF CAREER

Searle Scholar Award

UCSD Institutional Funds

Burroughs Wellcome Fund

March of Dimes Foundation

Kimmel Foundation

NSF

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference46 articles.

1. A genome-wide CRISPR death screen identifies genes essential for oxidative phosphorylation;Arroyo;Cell Metab.,2016

2. An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis;Birsoy;Cell,2015

3. Decoding directional genetic dependencies through orthogonal CRISPR/Cas screens;Boettcher;bioRxiv,2017

4. Quantitative analysis of aldolase A mRNA in liver discriminates between hepatocellular carcinoma and cirrhosis;Castaldo;Clin. Chem.,2000

5. Serine is a natural ligand and allosteric activator of pyruvate kinase M2;Chaneton;Nature,2012

Cited by 82 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Sensitive detection of synthetic response to cancer immunotherapy driven by gene paralog pairs;2024-07-04

2. HyCas9-12aGEP: an efficient genome editing platform for Corynebacterium glutamicum;Frontiers in Bioengineering and Biotechnology;2024-03-12

3. Role of functional genomics in identifying cancer drug resistance and overcoming cancer relapse;Heliyon;2024-01

4. An interpretable artificial intelligence framework for designing synthetic lethality-based anti-cancer combination therapies;Journal of Advanced Research;2023-12

5. A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics;Nature Communications;2023-11-13