Serine is a natural ligand and allosteric activator of pyruvate kinase M2-Reference-Cited by-同舟云学术

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

Published:2012-10-14 Issue:7424 Volume:491 Page:458-462
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Chaneton Barbara,Hillmann Petra,Zheng Liang,Martin Agnès C. L.,Maddocks Oliver D. K.,Chokkathukalam Achuthanunni,Coyle Joseph E.,Jankevics Andris,Holding Finn P.,Vousden Karen H.,Frezza Christian,O’Reilly Marc,Gottlieb Eyal

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature11540.pdf

Reference39 articles.

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3. Christofk, H. R. et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452, 230–233 (2008)

4. Altenberg, B. & Greulich, K. O. Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. Genomics 84, 1014–1020 (2004)

5. Mazurek, S., Boschek, C. B., Hugo, F. & Eigenbrodt, E. Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin. Cancer Biol. 15, 300–308 (2005)

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