C1 and N5 derivatives of cerpegin: Synthesis of a new series based on structure–activity relationships to optimize their inhibitory effect on 20S proteasome-Reference-Cited by-同舟云学术

C1 and N5 derivatives of cerpegin: Synthesis of a new series based on structure–activity relationships to optimize their inhibitory effect on 20S proteasome

Published:2013-05 Issue:9 Volume:23 Page:2696-2703
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hovhannisyan Anna,Pham The Hien,Bouvier Dominique,Qin Lixian,Melikyan Gagik,Reboud-Ravaux Michèle,Bouvier-Durand Michelle

Funder

French Association Against Myopathies

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

1. Exploiting nature's rich source of proteasome inhibitors as starting points in drug development

2. Proteasome Inhibitors: An Expanding Army Attacking a Unique Target

3. Proteasome Inhibitors: Recent Advances and New Perspectives In Medicinal Chemistry

4. A new series of N5 derivatives of the 1,1,5-trimethyl furo[3,4-c]pyridine-3,4-dione (cerpegin) selectively inhibits the post-acid activity of mammalian 20S proteasomes

5. STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

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