Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition

Author:

Hayek Simon,Pietrancosta Nicolas,Hovhannisyan Anna A.,Alves de Sousa RodolpheORCID,Bekaddour Nassima,Ermellino Laura,Tramontano Enzo,Arnould Stéphanie,Sardet Claude,Dairou Julien,Diaz Olivier,Lotteau Vincent,Nisole Sébastien,Melikyan Gagik,Herbeuval Jean-Philippe,Vidalain Pierre-OlivierORCID

Funder

Centre National de la Recherche Scientifique

Institut National de la Santé et de la Recherche Médicale

Université Saint-Esprit de Kaslik

Campus France

Agence Nationale de la Recherche

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference62 articles.

1. On dihydroorotate dehydrogenases and their inhibitors and uses;Munier-Lehmann;J. Med. Chem.,2013

2. Use of human dihydroorotate dehydrogenase (hDHODH) inhibitors in autoimmune diseases and new perspectives in cancer therapy;Lolli;Recent Patents Anticancer Drug Discov,2018

3. Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer;Madak;Pharmacol. Ther.,2018

4. The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor;O’Donnell;PLoS One,2010

5. Inhibition of dihydroorotate dehydrogenase overcomes differentiation blockade in acute myeloid leukemia;Sykes;Cell,2016

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3