Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer
Author:
Funder
UMCCC Core Grant
Publisher
Elsevier BV
Subject
Pharmacology (medical),Pharmacology
Reference221 articles.
1. cis-4-Carboxy-6-(mercaptomethyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-one, a potent inhibitor of mammalian dihydroorotase;Adams;Journal of Medicinal Chemistry,1988
2. Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting;Aguirre;Cancer Discovery,2016
3. Leflunomide suppresses growth in human medullary thyroid cancer cells;Alhefdhi;The Journal of Surgical Research,2013
4. In vivo inactivation by acivicin of carbamoyl-phosphate synthetase II in rat hepatoma;Aoki;Biochemical Pharmacology,1982
5. Phase I study of continuous-infusion PALA and 5-FU;Ardalan;Cancer Treatment Reports,1984
Cited by 147 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Discovery of piperine derivatives as inhibitors of human dihydroorotate dehydrogenase to induce ferroptosis in cancer cells;Bioorganic Chemistry;2024-09
2. Identification of isoquinolinone DHODH inhibitor isosteres;Bioorganic & Medicinal Chemistry Letters;2024-09
3. A Patent Review of Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors as Anticancer Agents and their Other Therapeutic Applications (1999-2022);Recent Patents on Anti-Cancer Drug Discovery;2024-08
4. Synergistic anticancer activity of Sulphoraphane and Teriflunomide co loaded lignin nanoparticles against triple negative breast cancer: Targeted nanoparticle delivery and drug repurposing;Medical Hypotheses;2024-08
5. Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer;Redox Biology;2024-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3