Benzenesulphonamide inhibitors of the cytolytic protein perforin-Reference-Cited by-同舟云学术

Benzenesulphonamide inhibitors of the cytolytic protein perforin

Published:2017-02 Issue:4 Volume:27 Page:1050-1054
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Spicer Julie A.,Miller Christian K.,O'Connor Patrick D.,Jose Jiney,Huttunen Kristiina M.,Jaiswal Jagdish K.,Denny William A.,Akhlaghi Hedieh,Browne Kylie A.,Trapani Joseph A.

Funder

Wellcome Trust

Auckland Division of the Cancer Society of New Zealand

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Perforin-mediated target-cell death and immune homeostasis

2. Cytotoxic T lymphocytes: all roads lead to death

3. Perforin and granzymes: function, dysfunction and human pathology

4. Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

5. The structural basis for membrane binding and pore formation by lymphocyte perforin

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