Perforin-mediated target-cell death and immune homeostasis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/nri1983.pdf
Reference141 articles.
1. Clark, W. R. Immunology. The hole truth about perforin. Nature 369, 16–17 (1994).
2. Kagi, D. et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369, 31–37 (1994). The importance of perforin in clearing virus-infected and transformed cells is shown for the first time using perforin-deficient mice.
3. van den Broek, M. E. et al. Decreased tumor surveillance in perforin-deficient mice. J. Exp. Med. 184, 1781–1790 (1996).
4. Kagi, D. & Hengartner, H. Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses. Curr. Opin. Immunol. 8, 472–477 (1996).
5. Katano, H. & Cohen, J. I. Perforin and lymphohistiocytic proliferative disorders. Br. J. Haematol. 128, 739–750 (2005).
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