Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists-Reference-Cited by-同舟云学术

Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists

Published:2007-08 Issue:16 Volume:17 Page:4415-4418
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Milbank Jared B.J.,Knauer Christopher S.,Augelli-Szafran Corinne E.,Sakkab-Tan Annette T.,Lin Kristin K.,Yamagata Koji,Hoffman Jennifer K.,Zhuang Nian,Thomas John,Galatsis Paul,Wendt John A.,Mickelson John W.,Schwarz Roy D.,Kinsora Jack J.,Lotarski Susan M.,Stakich Korana,Gillespie Kristen K.,Lam Wing W.,Mutlib Abdul E.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. A new series of pyridinyl-alkynes as antagonists of the metabotropic glutamate receptor 5 (mGluR5)

2. Structure–activity relationships for the linker in a series of pyridinyl-alkynes that are antagonists of the metabotropic glutamate receptor 5 (mGluR5)

3. Cyclohexenyl- and dehydropiperidinyl-alkynyl pyridines as potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists

4. Synthesis and Structure−Activity Relationships of 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Analogues as Potent, Noncompetitive Metabotropic Glutamate Receptor Subtype 5 Antagonists; Search for Cocaine Medications

5. Functionalization at position 3 of the phenyl ring of the potent mGluR5 noncompetitive antagonists MPEP

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