Synthesis and preliminary biological evaluation of a novel P2X7R radioligand [18F]IUR-1601-Reference-Cited by-同舟云学术

Synthesis and preliminary biological evaluation of a novel P2X7R radioligand [18F]IUR-1601

Published:2018-05 Issue:9 Volume:28 Page:1603-1609
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Gao Mingzhang,Wang Min,Glick-Wilson Barbara E.,Meyer Jill A.,Peters Jonathan S.,Territo Paul R.,Green Mark A.,Hutchins Gary D.,Zarrinmayeh Hamideh,Zheng Qi-Huang

Funder

Indiana University Showalter Young Investigator

Indiana University Department of Radiology and Imaging Sciences in the United States

United States National Science Foundation (NSF) Major Research Instrumentation Program

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

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2. The microglial ATP-gated ion channel P2X7 as a CNS drug target;Bhattacharya;Glia,2016

3. Molecular targets for PET imaging of activated microglia: The current situation and future expectations;Tronel;Int J Mol Sci,2017

4. Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [11C]A-740003 as a novel tracer of neuroinflammation;Janssen;J Labelled Comp Radiopharm,2014

5. Preclinical evaluation of a P2X7 receptor-selective radiotracer: PET studies in a rat model with local overexpression of the human P2X7 receptor and in nonhuman primates;Ory;J Nucl Med,2016

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