The microglial ATP-gated ion channel P2X7 as a CNS drug target-Reference-Cited by-同舟云学术

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The microglial ATP-gated ion channel P2X7 as a CNS drug target

Published:2016-05-24 Issue:10 Volume:64 Page:1772-1787
ISSN:0894-1491
Container-title:Glia
language:en
Short-container-title:Glia

Author:

Bhattacharya Anindya¹,Biber Knut²³

Affiliation:

1. LLC. Neuroscience Drug Discovery; Janssen Research & Development; 3210 Merryfield Row San Diego California

2. Department of Psychiatry and Psychotherapy; University Hospital Freiburg; Hauptstrasse 5 Freiburg Germany

3. Department of Neuroscience; University Medical Center Groningen, University of Groningen; Ant. Deusinglaan 1 AV Groningen The Netherlands

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Reference146 articles.

1. Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor;Abdi;Bioorg Med Chem Lett,2010

2. Receptor localization, native tissue binding and ex vivo occupancy for centrally penetrant P2X7 antagonists in the rat;Able;Br J Pharmacol,2011

3. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life;Ajami;Nat Neurosci,2007

4. Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects;Ali;Br J Clin Pharmacol,2013

5. The role of glutamate release mediated by extrasynaptic P2X7 receptors in animal models of neuropathic pain;Ando;Brain Res Bull,2013

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