Increased Cerebral Level of P2X7R in a Tauopathy Mouse Model by PET Using [<sup>18</sup>F]GSK1482160-Reference-Cited by-同舟云学术

Increased Cerebral Level of P2X7R in a Tauopathy Mouse Model by PET Using [¹⁸F]GSK1482160

Published:2024-05-22 Issue:11 Volume:15 Page:2112-2120
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Kong Yanyan¹,Cao Lei¹²,Wang Jiao³,Zhuang Junyi³,Liu Yongshan⁴,Bi Lei⁴,Qiu Yifan⁴,Hou Yuyi⁴,Huang Qi¹,Xie Fang¹,Yang Yunhao¹,Shi Kuangyu⁵,Rominger Axel⁵,Guan Yihui¹,Jin Hongjun⁴^ORCID,Ni Ruiqing²⁵⁶^ORCID

Affiliation:

1. PET Center, Huashan Hospital, Fudan University, Shanghai 200235, China

2. Institute for Regenerative Medicine, University of Zurich, Zurich 8952, Switzerland

3. Lab of Molecular Neural Biology, School of Life Sciences, Shanghai University, Shanghai 200444, China

4. Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, Guangdong 519000, China

5. Department of Nuclear Medicine, University Hospital, Inselspital Bern, Bern 3010, Switzerland

6. Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Zurich 8093, Switzerland

Funder

Natural Science Foundation of Shanghai

Helmut Horten Stiftung

Special Project for Research and Development in Key areas of Guangdong Province

National Natural Science Foundation of China

Science and Technology Innovation Plan Of Shanghai Science and Technology Commission

Guangdong Provincial Basic and Applied Basic Research Fund Provincial Enterprise Joint Fund

Swiss Center for Applied Human Toxicology (SCAHT)

Guangdong-Hong KongMacao University Joint Laboratory of Interventional Medicine Foundation of Guangdong Province

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.4c00067

Reference43 articles.

1. The P2X7 Receptor in Infection and Inflammation

2. Astrocyte adaptation in Alzheimer’s disease: a focus on astrocytic P2X7R

3. P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy

4. New role of P2X7 receptor in an Alzheimer’s disease mouse model

5. Role of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation “in vivo” by P2X7 receptor

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