The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia-Reference-Cited by-同舟云学术

The discovery of potent, selective, and orally active pyrazoloquinolines as PDE10A inhibitors for the treatment of Schizophrenia

Published:2012-01 Issue:2 Volume:22 Page:1019-1022
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ho Ginny D.,Yang Shu-Wei,Smotryski Jennifer,Bercovici Ana,Nechuta Terry,Smith Elizabeth M.,McElroy William,Tan Zheng,Tulshian Deen,McKittrick Brian,Greenlee William J.,Hruza Alan,Xiao Li,Rindgen Diane,Mullins Deborra,Guzzi Mario,Zhang Xiaoping,Bleickardt Carina,Hodgson Robert

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Second-Generation (Atypical) Antipsychotics and Metabolic Effects

2. Antipsychotics and QT prolongation

3. Chapter 1 Potential CNS Applications for Phosphodiesterase Enzyme Inhibitors

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