Identification of a new and diverse set of Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) inhibitors using structure-based virtual screening: Experimental validation and molecular dynamics studies

Author:

Raj Prateek,Selvam Karthik,Roy Koyel,Mani Tripathi Shailesh,Kesharwani Sharyu,Gopal Balasubramanian,Varshney Umesh,Sundriyal Sandeep

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference62 articles.

1. Global Tuberculosis Report 2021 World Health Organization; 202Licence: CC BY-NC-SA 3.0 IGO, Geneva (2021).; 202https://www.who.int/publications/i/item/9789240037021.

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3. Guardians of the mycobacterial genome: A review on DNA repair systems in Mycobacterium tuberculosis;Singh;Microbiology,2017

4. Focusing on DNA repair and damage tolerance mechanisms in mycobacterium tuberculosis: an emerging therapeutic theme;Mittal;Current Topics in Medicinal Chemistry,2020

5. The BER necessities: the repair of DNA damage in human-adapted bacterial pathogens;Van Der;Nature Reviews Microbiology,2015

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