Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy-Reference-Cited by-同舟云学术

Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy

Published:2008-06 Issue:11 Volume:18 Page:3392-3399
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hall Adrian,Billinton Andy,Brown Susan H.,Clayton Nicholas M.,Chowdhury Anita,Giblin Gerard M.P.,Goldsmith Paul,Hayhow Thomas G.,Hurst David N.,Kilford Ian R.,Naylor Alan,Passingham Barry,Winyard Lisa

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. Structure–activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists

2. The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain

3. 1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists: Structure–activity relationships of 4- and 5-substituted benzoic acid derivatives

4. 1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists. Structure–activity relationships of 6-substituted and 5,6-disubstituted benzoic acid derivatives

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