Structure–activity relationship studies of novel 3-oxazolidinedione-6-naphthyl-2-pyridinones as potent and orally bioavailable EP3 receptor antagonists-Reference-Cited by-同舟云学术

Structure–activity relationship studies of novel 3-oxazolidinedione-6-naphthyl-2-pyridinones as potent and orally bioavailable EP3 receptor antagonists

Published:2011-05 Issue:10 Volume:21 Page:2806-2811
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Morales-Ramos Ángel I.,Li Yue H.,Hilfiker Mark,Mecom John S.,Eidam Patrick,Shi Dongchuan,Tseng Pei-San,Brooks Carl,Zhang David,Wang Ning,Jaworski Jon-Paul,Morrow Dwight,Fries Harvey,Edwards Richard,Jin Jian

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

1. Prostanoid Receptors: Structures, Properties, and Functions

2. Prostanoid Receptors: Subtypes and Signaling

3. Prostaglandin E Receptors

4. Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation

5. Antagonists of the EP3 Receptor for Prostaglandin E2 Are Novel Antiplatelet Agents That Do Not Prolong Bleeding

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