Optimization of amide-based EP3 receptor antagonists-Reference-Cited by-同舟云学术

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Optimization of amide-based EP3 receptor antagonists

Published:2016-06 Issue:11 Volume:26 Page:2670-2675
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lee Esther C.Y.,Futatsugi Kentaro,Arcari Joel T.,Bahnck Kevin,Coffey Steven B.,Derksen David R.,Kalgutkar Amit S.,Loria Paula M.,Sharma Raman

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. The influence of drug-like concepts on decision-making in medicinal chemistry

2. Role of Physicochemical Properties and Ligand Lipophilicity Efficiency in Addressing Drug Safety Risks

3. Prostaglandin E Receptors

4. Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets

5. Enhanced bladder capacity and reduced prostaglandin E2-mediated bladder hyperactivity in EP3 receptor knockout mice

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. EP3 Receptor Deficiency Improves Vascular Remodeling and Cognitive Impairment in Cerebral Small Vessel Disease;Aging and disease;2022

2. Optimization of physicochemical properties of pyridone-based EP3 receptor antagonists;Bioorganic & Medicinal Chemistry Letters;2021-09

3. Discovery of a Novel Series of Pyridone-Based EP3 Antagonists for the Treatment of Type 2 Diabetes;ACS Medicinal Chemistry Letters;2021-02-26

4. The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity;Prostaglandins & Other Lipid Mediators;2019-10

5. Synthesis and PTP1B/TCPTP Inhibitory Activity Evaluation of Novel 2,5-Disubstituted-1,3,4-thiadiazolamide Derivatives Containing Carbazole/Benzimidazole Moity;Chinese Journal of Organic Chemistry;2019

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