Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists-Reference-Cited by-同舟云学术

Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists

Published:2009-06 Issue:11 Volume:19 Page:3072-3077
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Suzuki Takao,Moriya Minoru,Sakamoto Toshihiro,Suga Takuya,Kishino Hiroyuki,Takahashi Hidekazu,Ishikawa Makoto,Nagai Keita,Imai Yumiko,Sekino Etsuko,Ito Masahiko,Iwaasa Hisashi,Ishihara Akane,Tokita Shigeru,Kanatani Akio,Sato Nagaaki,Fukami Takehiro

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. Mice lacking melanin-concentrating hormone are hypophagic and lean

2. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

3. A role for melanin-concentrating hormone in the central regulation of feeding behaviour

4. Hypothalamic Pro-Opiomelanocortin mRNA Is Reduced By Fasting in ob/ob and db/db Mice, but Is Stimulated by Leptin

5. Differential Regulation of Melanin-Concentrating Hormone and Orexin Genes in the Agouti-Related Protein/Melanocortin-4 Receptor System

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