Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors-Reference-Cited by-同舟云学术

Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors

Published:2008-08 Issue:16 Volume:18 Page:4521-4524
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Zeng Li-Fan,Zhang Hu-Shan,Wang Yun-Hua,Sanchez Tino,Zheng Yong-Tang,Neamati Nouri,Long Ya-Qiu

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. Molecular mechanisms in retrovirus DNA integration

2. Integrase inhibitors to treat HIV/Aids

3. Novel aryl diketo-containing inhibitors of HIV-1 integrase

4. Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells

5. Raltegravir: an integrase inhibitor for HIV-1

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