A clickable photoaffinity probe of betulinic acid identifies tropomyosin as a target

Author:

Martín-Acosta Pedro,Meng Qianli,Klimek John,Reddy Ashok P.ORCID,David Larry,Petrie Stefanie Kaech,Li Bingbing X.,Xiao XiangshuORCID

Funder

National Institutes of Health

Oregon Health and Science University

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference52 articles.

1. Natural products as sources of new drugs from 1981 to 2014;Newman;J Nat Prod,2016

2. Polyterpenoid compouds. Part i. Betulinic acid from Cornus florida. L;Robertson;J Chem Soc,1939

3. Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection;Cichewicz;Med Res Rev,2004

4. Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis;Pisha;Nat Med,1995

5. Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors;Fulda;Cancer Res,1997

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3