Betulinic acid, a major therapeutic triterpene of Celastrus orbiculatus Thunb., acts as a chemosensitizer of gemcitabine by promoting Chk1 degradation
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology
Reference72 articles.
1. Pancreatic cancer chemoresistance to gemcitabine;Amrutkar;Cancers,2017
2. An ethnobotanical study on medicinal plants of Shexian Dryland Stone Terraced System in northern China;Bai;J. Ethnobiol. Ethnomed.,2022
3. Intracellular cytidine deaminase regulates gemcitabine metabolism in pancreatic cancer cell lines;Bjanes;Drug Metab. Dispos.,2020
4. Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells;Boudny;Haematologica,2019
5. Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78;Cai;Cell Death Dis.,2018
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