Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects

Author:

Wei Wei,Zeng Qingxuan,Wang Yan,Guo Xixi,Fan Tianyun,Li Yinghong,Deng Hongbin,Zhao Liping,Zhang Xintong,Liu Yonghua,Shi Yulong,Zhu Jingyang,Ma Xican,Wang Yanxiang,Jiang Jiandong,Song Danqing

Funder

National Natural Science Foundation of China

Chinese Academy of Medical Sciences

Publisher

Elsevier BV

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference55 articles.

1. Berberine and its role in chronic disease;Cicero;Adv Exp Med Biol,2016

2. Berberine in cardiovascular and metabolic diseases: from mechanisms to therapeutics;Feng;Theranostics,2019

3. Berberine for the treatment of hypertension: a systematic review;Suadoni;Compl Ther Clin Pract,2021

4. The metabolism of berberine and its contribution to the pharmacological effects;Wang;Drug Metab Rev,2017

5. Identification of berberine as a novel drug for the treatment of multiple myeloma via targeting UHRF1;Gu;BMC Biol,2020

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