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α-Tocopherol-ascorbic acid hybrid antioxidant based cationic amphiphile for gene delivery: Design, synthesis and transfection

  • Published:2019-02 Issue: Volume:82 Page:178-191
  • ISSN:0045-2068
  • Container-title:Bioorganic Chemistry
  • language:en
  • Short-container-title:Bioorganic Chemistry

Author:

Muripiti Venkanna,Brijesh Lohchania,Rachamalla Hari Krishnareddy,Marepally Srujan Kumar,Banerjee Rajkumar,Patri Srilakshmi V.

Funder

Department of Science and Technology, SERB-DST, Government of India, New Delhi, India

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference51 articles.

1. Gene therapy research in Asia;Deng;Gene Therapy,2017

2. Cystic fibrosis gene therapy: a mutation-independent treatment;Griesenbach;Curr. Opin. Pulm. Med.,2016

3. Gene therapy for the treatment of cystic fibrosis;Burney;Appl. Clin. Genet.,2012

4. Current status and future prospects for the treatment of lung disease in cystic fibrosis by gene therapy;Porteous;Pulm. Pharmacol.,1994

5. Transfection efficiency of cationic lipids with different hydrophobic domains in gene delivery;Zhi;Bioconjugate Chem.,2010

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