Phenylboronic acid-derived nanovectors for gene/drug delivery by targeting cell surface glycans

Author:

Muripiti Venkanna1ORCID,Ravula Venkatesh2,Batthula Srinivas3,Banothu Janardhan4ORCID,Gondru Ramesh5

Affiliation:

1. Department of Education, Central University of Kerala, Tejaswini Hills, Kasaragod-671320, Kerala, India

2. Laboratory of Self Assembled Biomaterials and Translational Science, Institute for Stem Cell Science and Regenerative Medicine (DBT-inStem), GKVK Post, Bellary Road, Bengaluru, 560065, Karnataka, India

3. Department of Pharmacy, Kangwon National University, Hyoja2-dong, Chuncheon, Republic of Korea

4. Department of Chemistry, National Institute of Technology Calicut, Kozhikode-673601, Kerala, India

5. Food Chemistry Division, ICMR–National Institute of Nutrition (NIN), Hyderabad-500007, Telangana, India

Abstract

Due to their high affinity for sialic acid (SA), which is commonly overexpressed in malignant cells, phenylboronic acid (PBA)-decorated nanoparticles efficiently transfer genes to the desired region. These nanoparticles can have unique applications in drug/gene delivery research.

Funder

Department of Science & Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Bio-Medical Applications of Carbon-Based Materials;Advances in Chemical and Materials Engineering;2024-06-28

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