Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics-Reference-Cited by-同舟云学术

Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics

Published:2021-04 Issue: Volume:109 Page:104661
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Li Hao,Illés Peter,Karunaratne Chamini V.,Nordstrøm Lars Ulrik,Luo Xiaoping,Yang Annie,Qiu Yunping,Kurland Irwin J.,Lukin Dana J.,Chen Weijie,Jiskrová Eva,Krasulová Kristýna,Pečinková Petra,DesMarais Vera M.,Liu Qiang,Albanese Joseph M.,Akki Ashwin,Longo Michael,Coffin Breyen,Dou Wei,Mani Sridhar,Dvořák Zdeněk

Funder

National Institutes of Health

Grantová Agentura České Republiky

U.S. Department of Defense

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference41 articles.

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3. The pregnane X receptor and its microbiota-derived ligand indole 3-propionic acid regulate endothelium-dependent vasodilation;Pulakazhi Venu;Am. J. Physiol. Endocrinol. Metab.,2019